Annotated Bibliography Cord Blood Banking

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  • Topic: Cord blood, Blood, Cord blood bank
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  • Published : April 17, 2013
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Annotated Bibliography

Waller-Wise, Rene. ncbi.nlm.nih.gov. Umbilical Cord Blood: Information for Childbirth Educators, Winter 2011. Web. 15 Feb. 2013.  
The author, a licensed clinical nurse specialist and childbirth educator, was driven to do research and write this article because she only had the basic information for cord blood banking to offer to couples is her classes. She shares that the first recipient of a cord blood transplantation was a 6-year-old boy who was treated for Fanconi's anemia using cord blood collected from his younger's sister's birth. She continues to list the disorders that stem cell transplants can treat. She discusses the advantages of using umbilical cord blood stem cells over bone marrow stem cells. A couple of reasons is that it is easier to collect and process and there is a decreased risk of transmission of infectious disease. One point she mentioned that was interesting and that I was not aware of was that if the pregnant woman had a history of group B streptococcus, active genital herpes, or prolonged rupture of membranes and chorioamnionitis, the umbilical cord is not saved. A disadvantage that the author points out is that cord blood is discarded in about 50% or more cases due to insufficient volume.  In addition to discussing private and public cord blood banks, the author brings to light the topic of direct-donation cord blood bank which accept autogenous donations and reserve them for the family whose infant has a sibling with a disorder. In this article, the author also shares professional organizations' s positions. She mentions that ACOG and AAP recommends the collection and banking of private cord blood only if a sibling or a family member has a medical diagnosis for which stem cells are currently being used for treatment.             I found this article very helpful because not only did the author share the benefits of cord blood stem cell transplantation, she brought to surface many of the limitations. I will particularly use the information about the percentage of cord blood that is discarded due to insufficient volume. Also, I will add the information about the conditions during pregnancy, labor and delivery that can affect the usability of the units.

Percer, Beth. "Umbilical Cord Blood Banking - Helping Parents Make Informed Decisions." Nursing for Women's Health (Volume 13, Issue 3): 217-223. Print.  
            In this article, the author discusses the potential benefits and drawbacks of cord blood transplantation. One of the benefits that she discusses is that there is a reduced risk of acute graft-versus-host reaction. One of the concerns is that a cord blood recipient cannot go back to the same infant donor to receive further cord blood stem cells. Another concern is the odds that children will need to use their own stem cells range from 1 in 400 to 1 in 200,000. It is because the cord blood stem cells may already have a genetic defect to the disease needing treatment.

The author also lists the drawbacks for private versus public banking. The negatives for public banking is that families will not have access to the stem cells in the future as they would have with private banking. This article also shows the different views of multiple respected organizations such as American Academy of Pediatrics (AAP), American College of Obstetricians and Gynecologists (ACOG), and World Marrow Donor Association (WMDA).             I will use the information in this article to discuss key points in my paper regarding benefits and negatives for stem cell transplantation and private versus public banking. In addition, I will include some of the organizations' views in my paper.

Journal of Midwifery & Woman's Health. "Share With Women." jmwh.org. Cord Blood Banking - What's It All About, 24 Dec. 2010. Web. 15 Feb. 2013.

This article breaks down exactly what Cord Blood Banking is. It looks specifically at what illnesses can be treated by stem cells, how...
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