Preview

Anaphylaxis

Powerful Essays
Open Document
Open Document
4222 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Anaphylaxis
The theme of this assignment is to explore the complex medical condition, anaphylaxis. Anaphylaxis is a severe allergic reaction that is potentially fatal. It is the clinical manifestation of a syndrome that represents the most severe allergic reaction affecting the systemic circulation and respiratory function (Resuscitation Council UK, 2005). Through a comprehensive examination of the symptoms displayed in the case study, a clear diagnosis will be recorded. Connections will be balanced between symptoms and the patient 's presenting condition. Physiological processes and mechanisms relating to the pathology will clearly explained through an in-depth discussion of disruptions to normal molecular, cellular, and organ functions that underlie the symptoms of the condition. Through debate and discussion, treatment will be deliberated in detail resulting in the provision of a gold standard, pre-hospital management plan.

Relationship Between Symptoms and Diagnosis

For the purpose of this assignment a paramedic working on a rapid response vehicle is called to a 46-year old female who is experiencing breathing difficulties. It is immediately apparent that the patient has a urticarial rash and a gross swelling to the lips, tongue and face. Whilst the patient is alert, it is clear that she is dyspenoeic. Primary observations confirm that the patient is tachycardic, tachypnoeic, hypoxic, and hypotensive. The patients’ blood glucose and temperature are within normal range. Due to the dyspnoea, it is

impossible to record a peak flow. Upon obtaining a thorough patient history, the paramedic discovers that the patient has just been prescribed Amoxicillin for a chest infection, she has no known allergies.

Whilst anaphylaxis seems likely, the initial differential diagnosis includes acute asthma, syncope and anxiety/panic attacks as many of the presenting symptoms are the same (Resuscitation Council 2006). For this reason, a more definitive guideline on rapidly diagnosing



References: ABBAS, A.K (2005) Diseases of immunity, 7th ed. Pilidelphia, Elsevier Saunders AACE, ASSOCIATION OF AMBULANCE CHIEF EXECUTIVES (2013) ANAPHYLAXIS CAMPAIGN (2014). Use of adrenaline inhalers http://www.anaphylaxis.org.uk/what-isanaphylaxis/knowledgebase/adrenaline-inhalers ANDERS, Diane, TRAUTMANN, Axel (2013). Allergic anaphylaxis due to subcutaneously injected heparin. Canadian Journal of Allergy and Clinical Immunology, 9 (1) ANDREAE (2009) http://www.bmj.com/content/339/bmj.b2489 BROWN SG (2005) http://www.priory.com/med/adrenaline.htm CAROLINE, Nancy (2008) CHOO KJL, SIMONS FER, SHEIKH A. (2009) Glucocorticoids for the treatment of anaphylaxis. Cochrane Database Syst Rev. 2009;1:CD007596. http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2010.02424.x/full FLOCKTON, Ruth (2007). Use of nebulised adrenaline in the management of steroid resistant stridor. Palliative Medicine, 21 (8) http://pmj.sagepub.com/content/21/8/723.extract GREAVES, IAN, et al. (2006) ‘Emergency Care’. A Textbook for Paramedics’. 2nd Edition. Saunders Elsevier. London GREGORY AND WARD 2010: Sanders Paramedic Textbook KEMP SF, LOCKEY RF (2002). Anaphylaxis: a review of causes and mechanisms. J Allergy Clin Immunol 2002;110:341-348 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683407/ KOBRYNSKI, Lisa (2007). Anaphylaxis. Clinical Paediatric Emergency Medicine, 8 (2), 110 – 116 http://www.clinpedemergencymed.com/article/S1522-8401(07)00027-4/fulltext LAXENAIRE MC. Epidemiology of anesthetic anaphylactoid reactions. Fourth multicenter survey (July 1994-December 1996)]. Ann Fr Anesth Reanim 1999;18(7):796-809. http://www.ncbi.nlm.nih.gov/pubmed/10486634 LEE, J.K., VADAS, P., (2011). Anaphylaxis: mechanisms and management. Clinical and Experimental Allergy, 41, 923 - 938 LONG A (2002) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC286326/ MULLER and HAERBERLI (2009) PUMPHREY RS, GOWLAND MH. Further fatal allergic reactions to food in the United Kingdom, 1999-2006. J Allergy Clin Immunol 2007;119(4):1018-9. http://www.ncbi.nlm.nih.gov/pubmed/17349682 RESUSITATION COUNCIL (2008) Emergency treatment for anaphylactic reactions: guidance for healthcare providers http://www.bmj.com/content/312/7023/71 SAMPSON et al, (2005) http://www.jacionline.org/article/S0091-6749(05)00032-1/abstract SHEIKH, A., et al (2007) SIMONS, F E, PETERSON, S, BLACK, C D. (2001b) Epinephrine dispensing for the out of hospital treatment of anaphylaxis in infants and children: a population based study. Ann Allergy Asthma Immunol. 86(6) 622–626. http://www.priory.com/med/adrenaline.htm SOUTH, MIKE, WILLIAMS, KATRINA (2012) http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1754.2012.02436.x/full STONE, SHELLEY AND BROWN, SIMON (2011) http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0002326 SNOWDEN, RACHEL (2009) WALKER, Tracey (2013). Study highlights need to study anaphylaxis prevention. Formulary, 48 (11) http://connection.ebscohost.com/c/articles/92036256/study-highlights-need-address-anaphylaxis-prevention http://www.ncbi.nlm.nih.gov/pubmed/24008815 ZHOU et al (2011)

You May Also Find These Documents Helpful

  • Satisfactory Essays

    Bee Stings Case Study

    • 258 Words
    • 2 Pages

    The health care provider prescribed the 8-year-old girl with a history of asthma and allergy to bee stings a course of penicillin to manage her current throat infection, and cautions her parents to watch her closely for her a reaction. The health care provider specifically provided her a prescription of penicillin to alleviate E.O.’s type I hypersensitivity to bee stings. The health care provider is concerned about the anaphylactic reaction that the little girl can have as a result of the prescription of penicillin. Penicillin is a common type of allergenic medication that can cause E.O. to have a life threatening allergic reaction. Type 1 hypersensitivity can result in an immediate reaction, which can occur between about 15…

    • 258 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    Hi, Tammy. Thank you for such an outstanding post this week. Have you ever cared for a child with the diagnosis of anaphylactic shock? My nephew has multiple food allergies including peanuts and cheese. Approximately one year ago his babysitter gave him a piece of regular cheese that was in the refrigerator instead of the special cheese that he was permitted to eat that was milk free. Consequently, he broke out in hives head to toe and began wheezing. There was an Epi-pen in the house. However, she forgot to use it. The ambulance came and administered the Epi-pen with minimal results. The dose was then repeated multiple times while he was transported to the hospital. Thankfully, after additional treatment at the hospital he survived. Due to…

    • 256 Words
    • 2 Pages
    Good Essays
  • Better Essays

    Case Study Anaphylaxi

    • 894 Words
    • 4 Pages

    Epinephrine is the best treatment for anaphylaxis and it works best if it is given within the first…

    • 894 Words
    • 4 Pages
    Better Essays
  • Good Essays

    Patient E.O.

    • 423 Words
    • 2 Pages

    Type 1 Hypersensitivity is a reaction that involves many parts of the body, for instance, the skin, eyes, nasopharynx, bronchopulmonary tissue, and the gastrointestinal tract. This reaction may cause a range of minor symptoms to fatality. Common manifestations that may possibly occur during Type 1 Hypersensitivity are rhinitis, asthma, atopic eczema, bee-sting reaction, and gastroenteritis. IgE, released from B cells, is an antibody that mediates hypersensitivity and arms mast cells, which exhibit as the principal component cell of this reaction in the body. The exposure of an allergen in an individual causes plasma B cells to produce the antibody IgE which circulates in small amount in the blood. Immunoglobulin E binds to the IgE receptors on mast cells which ultimately produces IgE antigen-binding sites on the surface of the mast cell. After the exposure of the mast cell with crosslinking of IgE-Fc receptors to an antigen, degranulation results and mediators are released causing signs of inflammation (Copstead & Banasik, 2010, pp. 227-228).…

    • 423 Words
    • 2 Pages
    Good Essays
  • Powerful Essays

    “I have asthma attacks, but otherwise feel good. I’m still having problems with my left leg but I’m working on it”…

    • 2420 Words
    • 10 Pages
    Powerful Essays
  • Powerful Essays

    Nursing Npr

    • 2728 Words
    • 11 Pages

    References: Ackley, B., & Ladwig, G. (2006). Nursing Diagnosis Handbook (7th ed.). St. Louis, MO:…

    • 2728 Words
    • 11 Pages
    Powerful Essays
  • Satisfactory Essays

    peanut allergy

    • 503 Words
    • 3 Pages

    Reveal The Topic: The case above occur from the peanut allergy. Peanut allergy is one of the most serious of the direct allergic reactions to foods in terms of persistence.…

    • 503 Words
    • 3 Pages
    Satisfactory Essays
  • Powerful Essays

    Peanut Allergies

    • 2112 Words
    • 9 Pages

    At some point in our lives, we have done something or possibly will do something that has felt as though a panic attack or shortness of breathe has been triggered off. Was it excitement? Was it anxiety? What was causing it? For millions of Americans and people world wide it’s very possible that all of this was being brought on by an allergy to something that had been eaten, or something that has been eaten in the past that your immune system didn’t built a tolerance to. Enter peanut allergies. According to most scientists and researchers; peanut allergies may be one of the most life threatening of all food allergies if the allergy is not detected early on in life (Young 2). Like most of us when we were kids we have come to adapt or grow out of things that were inherited by our parents, better known as natural selection. Peanut Allergies are increasing and the cause of it is still a mystery; however, there are possible solutions to avoid this anaphylaxis epidemic.…

    • 2112 Words
    • 9 Pages
    Powerful Essays
  • Good Essays

    Anaphylactic shock is a allergic reaction when someone's immune system releases chemical that floods the body. When going into anaphylaxis shock your blood pressure drops suddenly and airways narrow. This is common in humans and animals. It is caused when someone eats food that they are allergic to. Common causes include foods such as peanuts, tree nuts, almonds, walnuts, cashews, and brazil nuts. Also sesame, fish, shellfish, dairy products and eggs.…

    • 1014 Words
    • 5 Pages
    Good Essays
  • Good Essays

    While most schools and households have peanuts in their homes and schools. Most people do not know the severe risk that could harm someone else around you. A book written by Doctor Michael C. Young states that food allergies affect eight percent of children under three and six to eleven percent of school age children, and only fifty percent of children outgrow milk and egg allergies by the age of six, but only ten percent outgrow peanut allergy by the age of nine. The prevalence of peanut and tree nut allergies in children has doubled in the past five years. Seventy-five percent of peanut-allergic reactions occur on the first know exposure. In the United States fatal food anaphylaxis occurs in one-hundred people each year often outside the home, in schools and restaurants. Given these shocking statistics, every school needs to be prepared to deal with the problem of food anaphylaxis, especially from peanut allergy.…

    • 1186 Words
    • 5 Pages
    Good Essays
  • Good Essays

    Pediatric Allergies

    • 565 Words
    • 3 Pages

    Allergen tests are performed on the skin by using a minute sample of the suspected allergen. Blood tests can also be taken, but are more expensive than skin tests. Treatment is fairly straightforward and that is avoiding the allergen. If it is impossible to completely avoid the substance causing the reaction, then pharmacotherapy may alleviate the symptoms. Long-acting histamines are drugs of choice in addition to others that can treat and prevent inflammation. There are also allergy vaccines that may be given over a period of months, which may be given to help strengthen the patient’s tolerance to the…

    • 565 Words
    • 3 Pages
    Good Essays
  • Good Essays

    | Metronidazole (Flagyl) 500mg by mouth every eight hours.Lisinopril (Zestril) 20mg by mouth once a day.Timolol (Timoptic) 0.5% one drop to both eyes twice a day.…

    • 691 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Food Allergies In Infants

    • 1491 Words
    • 6 Pages

    The complex process of digestion affects the timing, location, and particular symptoms of an allergic reaction to food. All of the symptoms of food allergy occur within a few minutes to an hour of eating. A food allergy can initially be experienced as an itching of the tongue, a swollen tongue, difficulty swallowing and breathing. Then, during digestion of the food in the stomach and intestines, symptoms such as nausea, vomiting, diarrhea, and abdominal pain can start. Incidentally, the gastrointestinal symptoms of food allergy are those that are compared to the symptoms of different types of food intolerance.…

    • 1491 Words
    • 6 Pages
    Good Essays
  • Powerful Essays

    An Assessment of Asthma

    • 1591 Words
    • 5 Pages

    Kennedy, S. (2006). Assessment of a patient with an acute exacerbation of asthma. Nursing Standard, 21(4), 35-38.…

    • 1591 Words
    • 5 Pages
    Powerful Essays
  • Good Essays

    Allergic Rhinitis Essay

    • 467 Words
    • 2 Pages

    Allergic rhinitis is a chronic respiratory disease characterized by inflammation of the nasal cavity and affects people of all ages. The main symptoms of allergic rhinitis are sneezing, nasal itching, blocked or runny nose and sore throat. Research suggests that a combination of genetic factors such as family history of allergic rhinitis and environmental factors such as exposure to allergens, including smoke, dust, pollen, insects, molds, or animal dander, may increase the risk for developing allergic rhinitis. According to the World Health Organization, an estimated 400 million people worldwide were affected with allergic rhinitis during 1996-2006.…

    • 467 Words
    • 2 Pages
    Good Essays

Related Topics