An Investigation of Vibrio Cholera

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An Investigation of Vibrio cholera

Frank Makridakis
December 10th, 2010

I chose to investigate Vibrio cholerae from the genus Vibrio because I found that V. cholerae was a very interesting bacteria. According to our textbook, (Prescott's Principles of Microbiology by Willey Joanne, Woolverton Chris, Sherwood Linda), V. cholerae has caused seven pandemics in various parts of the world, especially Asia, the Middle East and Africa. According to the 2009 Cholera annual report from the World Health Organization, (Weekly Epidemiological Record, 2010, 85(31):293-308), the US experienced less than 20 cases while around the world 45 countries experienced 221226 cases including 4946 deaths. In 1883 Robert Koch, who is considered by our text and many others to be one of the founders of microbiology identified the Vibrio bacterium that caused cholera. Koch believed that the key to prevention was to improve hygiene and in sanitary drinking water. This is the reason that there are so few cases in the United States per year, because we have a high degree of sanitary drinking water throughout the United States. Our textbook describes its taxonomy as being one of many serogroups, the textbook identifies V. cholerae O1 and 0139 to be one of two serogroups that cause epidemics. V. cholerae O1 also has two sterotypes and two biotypes. In 1992, the new strain, 0139 was discovered in Asia, but for the first time in recorded history, the 0139 strain actually displaced the 01 serogroup in India. Some of the genus Vibrio characteristics are that they are capable of fermentative and oxidative metabolism. According to Bergey’s Manual, they are related to enteric bacteria and Pseudomonadaceae and they are considered to be "Facultatively Anaerobic Gram-negative Rods" and on the level with the Family Enterobacteriaceae. Vibrios are distinguished from enterics by being oxidase-positive and motile by means of polar flagella. V. cholerae as infectious bacteria, have the same...
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