Alagille Syndrome

Only available on StudyMode
  • Download(s) : 53
  • Published : April 27, 2013
Open Document
Text Preview
Alagille Syndrome

Abstract
Alagille syndrome is a genetic disorder passed either by the parents or due to a genetic mutation(s). The liver is the affected region of the body. The liver has a lower count of bile ducts within the liver resulting in liver damage due to buildup of bile. If the liver stops working a transplant is needed for the patient to survive. This disorder also affects many other systems of the body. Treatment options include either use drugs or a liver transplant. There is no genetic cure for Alagille syndrome.

Introduction:
Alagille syndrome is a genetic disorder passed through the parents. The liver is where the disease is located and it is seen when the liver has a lower count of bile ducts within the liver. Since there are too few bile ducts the liver cannot carry bile out of the liver resulting in liver damage due to the buildup. Once the liver stops working a transplant is needed immediately. This disorder also affects many other systems of the body and these will warrant a visit to the pediatrician. The only way to stop Alagille syndrome affects in the liver is to either use drugs or have a liver transplant. Characteristics:

The characteristics of Alagille reside all throughout the body. Whether it shown in the mutated genes or a side effect such as a heart murmur. The Alagille syndrome affects all parts of the body in all ways. It can stop proper growth due to Malabsorption or cause swelling of the kidneys due to bile buildup. This syndrome can be deadly if not taken care of. This syndrome is a hindrance and affects one in every 70,000 births worldwide and prominent within the first two years of an infant’s life.

Causes:
The Alagille syndrome is genetic. When a child has a parent with this genetic disorder there is a fifty percent chance that the child will receive this defect. The percentage of a child having Alagille syndrome with both parents having the disorder is unknown because there have been no cases reported of...
tracking img