Preparation of Potassium Chloride 10% (W/V) Oral Solution

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Preparation of Potassium Chloride 10% (w/v) Oral Solution

Questions:

1.One source of potassium chloride occurring in nature is carnallite. What is its chemical formula? What are the others sources of potassium chloride? KMgCl3• 6H2O
Other sources:
Sylvite
Halite

2.What are the therapeutic uses of potassium chloride?
-drug used to maintain or restore potassium levels in patients with potassium deficiency, which can cause such problems as thirst, fatigue, low blood pressure, muscle cramps, nausea, and irregular heartbeat. Some diuretics (medications that increase urination) and heart drugs, as well as certain diseases, can cause potassium deficiency. Potassium chloride works by controlling the body’s water balance and regulating such processes as nerve transmission, muscle contraction, and normal heart rhythm.

3.What is the disadvantage of taking potassium chloride solution orally? • The advantage of oral potassium to avoid the use of glucose and sodium chloride injection or intravenous drip at the role of potassium offset their disadvantages can lead to abdominal discomfort, nausea and other gastrointestinal reactions. ) oral have gastrointestinal symptoms, such as nausea, vomiting, throat discomfort and chest pain (esophageal irritation), abdominal pain, diarrhea, and even peptic ulcer bleeding. In fasting, and the original large dose of gastrointestinal diseases more likely.

4.If solid potassium chloride will be used orally, how should it be taken? • Oral: Sustained release and wax matrix tables should be swallowed whole, do not crush or chew; effervescent tablets must be dissolved in water before use; administer with food; granules can be diluted or dissolved in water or juice; do not administer liquid full strength, must be diluted in 2-6 parts of water or juice. 5.Give the different concentrations of potassium chloride oral solution in terms of % and meq/ml. •Potassium Chloride Oral Solution, USP 10%: 20 mEq of...
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