Hartwell Genetics Ch. 13 Study Guide

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Chapter 13—Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryote Genomes

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|1. |Events that reshape genomes by reorganizing the DNA sequences within one or more chromosomes are known as ____________________. | |Ans: |rearrangements | | |Difficulty:  2 |

|2. |____________________, duplications, inversions, translocations, and movements of transposable elements are all types of | | |rearrangements of chromosomal material. | |Ans: |Deletions | | |Difficulty:  2 |

|3. |Very large deletions are visible at the relatively low resolution of a __________________, showing up as the loss of one or more| | |bands from a chromosome. | |Ans: |karyotype | | |Difficulty:  2 |

|4. |Changes in gene ____________________, the number of times a given gene is present in the cell nucleus, can create a genetic | | |imbalance. | |Ans: |dosage | | |Difficulty:  3 |

|5. |An unpaired bulge of one member of a homologous pair of chromosomes during prophase of meiosis I is known as a | | |____________________. | |Ans: |deletion loop | | |Difficulty:  3 |

|6. |A recessive mutation in the mouse that prevents homozygous animals from walking in a straight line is known as the | | |____________________ gene. | |Ans: |shaker-1 | | |Difficulty:  3 |

|7. |When repeats of a region lie adjacent to each other they are called ____________________ duplications. | |Ans: |tandem | | |Difficulty:  2 |

|8. |Inversions that include the centromere are termed ____________________. | |Ans: |pericentric...
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