Drugs and Chemicals

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Drugs and Chemicals to be Avoided in G6PD Deficiency
Drugs to be Avoided in G6PD Deficiency
There are different types of G6PD deficiency, an individual need to know the type of G6PD that they have inherited because each types of G6PD deficiency react to drugs differently and some may not react to some of the drugs and chemicals listed here. This is not a comprehensive list there are drugs and chemicals that may also be harmful to those with G6PD deficiency that are not on this list an individual should always consult their doctor for advice before taking any medication. Generic NameTrade NameIndication

Acetanilide-Once used as analgesic/antipyretic

Methylene Blue-Methaemoglobinaemia

Naphthalene-Lavatory deodorant
Old fashioned mothballs

Nalidixic AcidMictralUrinary tract infection
Negram

Uriben

NidazoleAmbilharSchistosomicide

NitrofurantoinBerkfurinUrinary tract infection
Ceduran

Furadantin

Furan

Macrodantin

Urantoin

PamaquinePlasmoquineOnce used as an antimalarial

Pentaquine-Antimalarial

Primaquine-Antimalarial

SulphanilamideRhinamidNasal drops, vaginal cream

SulphacetamideAlbucidEye infections
Bleph-10 Liquifilm

Cortucid

Isoptocetamide

Minims

Ocusol

Sulfaped

Sulphacalyre

SultrinVaginal infections

SulphapyridineM & B 693Dermatitis, herpetiformis

Sulphamethoxazole Combination ProductsCo-TrimoxazoleUrinary tract infections
Bactrin

Chemotrim

Comox

Contrimox

Fectrim

Laratrim

Septrin

ThiazosulphonePromizoleOnce used for leprosy

Drugs to be Used with Some Caution in G6PD Deficiency
A list of drugs is given in this section which might cause jaundice and anaemia in G6PD deficiency. Some of the drugs would do this if taken in too high doses; some could do so if taken for treatment of infections. If any of the drugs listed are being taken by patients it is important to check that the drug is not causing jaundice and anaemia. As with the list of drugs known to provoke haemolysis, those in italics are available in the UK. Generic NameTrade NameIndication

AcetaminophenParacetamolAnalgesic, antipyretic
Combination Products

Calpol

Carisoma Co

Cosalgesic

Delimon

Dextrogesic

Dimotapp P

Distalgesic

Femerital

Fortagesic

Lobak

Medised

Migraleve

Myolgin

Norgesic

Paradeine

Paragesic

Paramax

Paramol

Parazolidin

Paxidal

Pharmidone

Pholcolix

Propain

Paedo-Sed

Paldesic

Pameton

Panadol

Panasorb

Rinurel (SA)

Safapryn (Co)

Salzone

Sudafed

Syndol

Tandalgesic

Triogesic

Tritussic

Uniflu

Veganin

Combination with Caffeine

Cafadol

Panadeine Co

Paracodol

Parake

Medocene

Neurodyne

Unigesic

Combination with Caffeine and Codeine

Parahypon

Paralgin

Pardale

Solpadeine

Acetophenetidine*PhenacetinAnalgesic, antipyretic

* This drug is now banned in the UK except by special prescription from a doctor or dentist

Amidopyrine, orAreumalAnalgesic, antiflammatory
AminopyrineBaukal

AminophenazoneBudirol

AminophenazoniumDepiral C

AmidazofenFenodone

Amidopyrine-PyramidonFever

Dimethylamino AntipyrineFtalazone

DimethylaminophenazoneGalenopyrine

Glucopirina

Hyparon

nst

Isoftal

Katareuma

Latepyrine

Metopirazone

Netsusarin

p-Aminobenzoic AcidTopical sunscreen agent

AnatazolineAntistin-PrivineNasal and eye drops for allergies
Otrivine Antisin

RBC

Vasocon-A

Ascorbic AcidThere is large numbers of pharmaceutical products containing ascorbic acid. These range from simple ascorbic acid tablets to multivitamin preparations. Unless large doses of ascorbic acid are taken...
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