Cbc Parameters

Topics: Immune system, Inflammation, White blood cell Pages: 6 (726 words) Published: May 1, 2013
CBC w/ Differential
CBC w/ Differential
Fight infection
Attack foreign material
4500-17000
Lifespan= hours-days

Fight infection
Attack foreign material
4500-17000
Lifespan= hours-days

WBC
Elevated: Infection, tissue necrosis, bone marrow malignancies, inflammation Decreased: infection, medications that suppress or weaken the immune system or bone marrow WBC
Elevated: Infection, tissue necrosis, bone marrow malignancies, inflammation Decreased: infection, medications that suppress or weaken the immune system or bone marrow

Increased (neutrophilia):
Bacterial infection, inflammatory conditions, tissue damage, malignancies of the bone marrow *Increased neutrophils in general: bacterial infection.
*Rise in bands in particular is highly suggestive of bacterial infection. Increased (neutrophilia):
Bacterial infection, inflammatory conditions, tissue damage, malignancies of the bone marrow *Increased neutrophils in general: bacterial infection.
*Rise in bands in particular is highly suggestive of bacterial infection.

Decreased (monopenia):
Some forms of leukemia, bone marrow failure or suppression

Decreased (monopenia):
Some forms of leukemia, bone marrow failure or suppression

Increased (monocytosis):
Monocytic leukemia, ulcerative colitis, viral diseases (mononucleosis and herpes zoster), parasitic diseases (Rocky Mountain Spotted Fever) Increased (monocytosis):
Monocytic leukemia, ulcerative colitis, viral diseases (mononucleosis and herpes zoster), parasitic diseases (Rocky Mountain Spotted Fever) B Lymphocytes (B Cells): humoral immunity
T Lymphocytes (T Cells): cell-mediated immunity
B Lymphocytes (B Cells): humoral immunity
T Lymphocytes (T Cells): cell-mediated immunity
Decreased (neutropenia):
Vital conditions, overwhelming infection that exhausts bone marrow, cancer drugs, antibiotics and psychotropic drugs, hereditary disorders *Newborns with sepsis are higher risk for developing neutropenia. Decreased (neutropenia):

Vital conditions, overwhelming infection that exhausts bone marrow, cancer drugs, antibiotics and psychotropic drugs, hereditary disorders *Newborns with sepsis are higher risk for developing neutropenia. First line of defense against infection

Bands (immature) 0%
Segs (mature) 31-57%
First line of defense against infection
Bands (immature) 0%
Segs (mature) 31-57%
-Second line of defense against infection
-Indicates viral infection
-Second line of defense against infection
-Indicates viral infection
Monocytes
(4-7%)
Monocytes
(4-7%)
“Right shift”
-Rise in monocytes and lymphocytes
-Viral infection

“Right shift”
-Rise in monocytes and lymphocytes
-Viral infection

“Left shift”
-Increase in bands
-Indicates bacterial infection
“Left shift”
-Increase in bands
-Indicates bacterial infection
Neutrophils
(31-57%)
Neutrophils
(31-57%)

Increased (lymphocytosis):
Viral infections (most common), bacterial or allergic conditions (least common) Increased (lymphocytosis):
Viral infections (most common), bacterial or allergic conditions (least common) Decreased (lymphopenia):
Corticosteroid therapy, adrenocortical hyperfunction, stress, shock

Decreased (lymphopenia):
Corticosteroid therapy, adrenocortical hyperfunction, stress, shock

Indicates viral infection
Indicates viral infection
Lymphocytes
(35-61%)
Lymphocytes
(35-61%)
Eosinophils
(2-4%)
Eosinophils
(2-4%)
Indicates allergic disorders and parasitic infections
Indicates allergic disorders and parasitic infections
Increased (eosinophilia):
Asthma, hay fever, drug reaction
Increased (eosinophilia):
Asthma, hay fever, drug reaction
Decreased (eosinopenia):
Corticosteroid therapy, adrenocortical hyperfunction, stress, shock Decreased (eosinopenia):
Corticosteroid therapy, adrenocortical hyperfunction, stress, shock Indicated systemic allergic reactions
Responsible for histamine release
Indicated systemic allergic reactions
Responsible for histamine release...
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